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Serotonin syndrome: The use of SSRIs and SNRIs can lead to this potentially fatal condition.

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For treatment of chronic pain in patients with depression, clinicians should strongly consider using tricyclic or SNRI antidepressants for analgesic as well as antidepressant effects if these medications are not otherwise contraindicated (see Recommendation 1).

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Efficacy of duloxetine on cognition, depression, and pain in elderly patients with major depressive disorder: an 8-week, double-blind, placebo-controlled trial.

This section includes symptom scores, symptom questionnaires, scales, indexes, patient reported outcome measures (PROMs) and health-related quality of life (HRQoL) measures.

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